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NARASIN

 

 

 

BROILER 

At 140 ppm reduction of the daily weight gain of 8 % versus 80 ppm.

At 240 ppm reduction of the feed consumption and growth of 30%, histopathological lesions in the muscle.

At 400 ppm mortality of 17%.

 

LAYING AND BREEDER PULLET

No information.

 

 

LAYING HEN  

Residue in the eggs, reduction of laying at 70 ppm.

20 ppm does not affect the production.

 

BREEDER HEN 

Reduction of the laying and of the hatchability at 70 ppm.

 

TURKEY

Mortality at 70 ppm.

 

DUCK 

No negative results at 68 ppm for 28 days.

 

GUINEA FOWL

Toxic.

 

PHEASANT  

No negative results at the usual dose.

 

QUAIL

No negative results up to 50 ppm for 5 days, prostration, ataxia above.

 

PARTRIDGE 

No information.

 

RABBIT 

At 10 - 36 ppm : 34 to 40% mortality, lack of co-ordination and paralysis.

 

HORSE 

LD50 = 1 mg/kg LW.

Very toxic at the common dose, mortality when the dose exceeds.

 

CATTLE 

LD0* = 5 mg/kg LW.

Reduction of the consumption and the daily weight gain from 0.5 mg/kg LW.

Mortality at 4 mg/kg LW after 6 days.

 

SHEEP

40 - 50 ppm for a few days caused dyspnoea, posterior weakness  lack of co-ordination, prostration, muscular toxicity.

 

SWINE 

LD50=8 mg/kg LW from a single oral dose

5 mg/kg LW showed ionophore toxicity (emesis, dyspnoea, ataxia, death)

 

 

 

* LD0= Minimum fatal dose at single administration.