<Return to Previous Screen>

MONENSIN

BROILER	LD50 = 200 mg/kg LW. 1.5 to 2 times the usual dose for 3 weeks = loss of weight. 3 to 6 times the usual dose = reduction of the daily weight gain, feed consumption, mortality. Decrease of water consumption. In warm circumstances : reduction of feed consumption.
LAYING AND BREEDER PULLET	Authorised for growing breeder hens.
LAYING HEN	Residue in the eggs.
BREEDER HEN	At 100 ppm reduction of fertility (Jones – 1990).
TURKEY	LD50 = 335 mg/kg LW for the young ones. 200 – 300 ppm at 7-8 weeks : decrease of weight and of the feed consumption from 13 to 24% (Potter & al –1986) For the full grown : <100 ppm continuously = mortality (Halvorsen & al – 1982).
DUCK	No negative results at 2 times of the usual broiler dose (Perlstein –1984), paralysis at 158 ppm for the Pékin duck(Reece – 1988).
GUINEA FOWL	Paralysis, mortality at the usual broiler dose (Reece – 1988).
PHEASANT	No negative results at the usual dose (Jurkovic – 1982).
QUAIL	No negative results at the usual dose.
PARTRIDGE	No negative results at the usual dose.
RABBIT	Toxic at 100 ppm. LD50 = 40 mg/kg LW.
HORSE	DLD50 = 2 mg/kg LW (it means 10 kg of a broiler feed for a 500 kg horse). External signs : ataxia, paralysis, salivation, cardiac myopathy , mortality.
CATTLE	Authorised. From 40 to 100 ppm : anorexia, decrease of growth. Very high toxic at 6-10 the dose recommended for cattle. LD50 = 25 mg/kg LW.
SHEEP	LD0* = 4 mg/kg LW. During 3 month : 22 ppm without negative results. At 66 ppm : 10% of cardiac injury. At 110 ppm : 10% of mortality.
SWINE	LD50 = 16 – 50 mg/kg LW.

*LD0= Minimum fatal dose at single administration.