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AVATEC (lasalocid sodium)

BROILER	No negative results form feeding twice the recommended dose for 3 weeks. : For ‘Label’ broiler breeders with a dwarf gene locomotion disorders may occurs. To avoid this risk : use Avatec at 75 ppm for 4 weeks, then 90 ppm.
LAYING AND BREEDER PULLET	Restricted feeding : 105 pm from 0 to 8 weeks, then 90 ppm Ad libitum feeding : 90 ppm from 0 to 8 weeks, then 75 ppm Replacement laying hen : 105 ppm from 0 to 8 weeks, then 90 ppm Intolerances have been observed at dwarf breeds type JV15, JA57.
LAYING HEN	No negative effects on the hen up to 150 ppm, and no effect shown on the weight of the eggs at 75 ppm. Residue in the eggs at 3 ppm in the feed.
BREEDER HEN	At 75 ppm a reduction of the hatchability and the fertility, back to normal after withdrawal.
TURKEY	No negative results when fed continuously up to 16 weeks at 375 ppm, 4 times the usual dose. (Lodge &et al- 1988) Adults : no negative results at 12 ppm when started at 13 or 40 weeks old.
DUCK	No negative results at 2 times the usual dose ( Perlstein & al 1984).
GUINEA FOWL	No negative results at 187.5ppm (Hamet- 1981)- Anti coccidial effective on E. grenieri at 200 ppm.
PHEASANT	Very good anti coccidial at 100-120 ppm (Jurkovic & al – 1982). Authorised in the UK at 90-120 ppm up to 12 weeks.
PARTRIDGE	Idem pheasant. Authorised in USA at 125 ppm up to 8 weeks.
RABBIT	No negative results at broiler dose Authorised in USA at 125 ppm up to 6 weeks.
HORSE	LD50= 21.5mg/kg LW, a good level of safety compared to other ionophores, for a horse of 500kg this is equal to 100kg of feed at 100 ppm. In general the feed is unpalatable.
CATTLE	Young cattle : No negative results up to 2.2mg/kg LW in a single dose. Used as a growth promoter in USA at 33 ppm or a dose of 1 mg/kg LW/d(maximum : 360 mg/animal/day).
SHEEP	No negative results at 75-125 ppm.,
SWINE	No negative results up to 21 mg/kg LW in a single dose. At 35 mg/kg LW weakness of the muscles. At 58 mg/kg LW mortality.